EKC2024

DIVISIONS

Life Science and Health

The Life Science and Health division will reflect the contemporary trends in the area. As life sciences evolve, they are increasingly multidisciplinary, mirroring trends seen in other modern science areas. Therefore, our sessions will cover overarching themes that encompass not only ‘pure’ biological sciences, life sciences and health research but also highly multidisciplinary topics combined with other areas such as computations, artificial intelligence, data science, information technology, material science, other engineering sciences, and physical sciences. LH sessions will provide the experts from Korea and Europe with opportunities to engage in discussions about the latest progress in these ever-changing areas and foster connections for future collaboration. We invite presentations covering the following areas: • One Health: understanding diseases and pathogens • Aging and Diseases • Cutting-edge Technology to Fight Against Vision-threatening Diseases • Exploring Multifaceted Approaches to Reducing the Cancer Burden and Promoting Health • Cell Plasticity and Homeostasis: Unraveling Multipotency in Health and Disease • Many Ways to Address the Antimicrobial Resistance Issue • Excellence with Impact: Disruptive Innovations in the Biomedical Space • New Ideas and Approaches in Biological Sciences

Programme Committee

DR. LEE, Seung Seo (이승서)

School of Chemistry, University of Southampton

s.s.lee@soton.ac.uk

Show Profile

Dr Seung Seo Lee is Associate Professor of Chemical Biology/Medicinal Chemistry, conducting cutting-edge research projects at the interface of chemistry and biology on antimicrobial resistance and glycoenzymes. Dr Lee obtained his BSc and MSc in chemistry from Seoul National University in Seoul, Korea. He then worked in the pharmaceutical industry before starting his doctoral study in chemistry at University of British Columbia in Vancouver, Canada. He obtained his PhD under the supervision of Professor Stephen G Withers, studying the reaction mechanism of glycan processing enzymes. After postdoctoral studies at University of Cambridge (Prof. Florian Hollfelder),  University of Alberta (Prof. David R Bundle) and University of Oxford (Prof. Benjamin G Davis), he has been working at the School of Chemistry, University of Southampton, initially as assistant professor and now associate professor.

DR. LEE, Kyung Min (이경민)

Finnish Museum of Natural History, University of Helsinki

kyung.m.lee@helsinki.fi

Show Profile

Dr Kyung Min Lee is the Head of the DNA laboratory and University Researcher at the Finnish Museum of Natural History (LUOMUS), University of Helsinki, Finland. Her expertise lies in molecular phylogenetics and systematics, with a particular focus on biodiversity research utilising old museum collections. Dr Lee is dedicated to unraveling genome-scale biodiversity patterns, exploring cryptic/over-split species, and applying “museomics” to tackle taxonomically challenging species groups. She is pioneering a novel approach using machine learning for more objective species delimitation. She received PhD degree from the Department of Biology at Chungnam National University, Daejeon, Korea. Following her doctoral studies, she pursued postdoctoral research at Ghent University in Belgium, supported by a fellowship from the NRF funding. Later, in 2015, she moved to Finland to join the University of Oulu, where she focused on the study of the next-generation taxonomy in various organisms. In 2020, Dr Lee was recruited to LUOMUS, Helsinki, where she continues her academic endeavors to date.

[LH0] Innovative Technology for Protein Engineering and Science & (Round table) Europe-Korea Partnership: Advancing Frontiers in Biosciences and Biotechnology

Date / Time	2024-07-30 09:00 -- 10:40
Room	OC1.04
Conveners / Chairs	DR. WOO, Eui-jeon Principal Scientist at the Disease Target Structure Research Center, KRIBB Show Profile Dr. Eui-Jeon Woo is a Principal Scientist at the Disease Target Structure Research Center, KRIBB, and an adjunct professor of proteomics and structural biology at the University of Science and Technology (UST), Korea. He specializes in protein and enzyme structure and function, currently focusing on protein design using computational biology and chemistry for pharmaceuticals. In 2022, he received the Order of Science and Technology Merit (Doyak-jang) from the Korean government. DR. LEE, Kyung Min Head of the DNA laboratory at the Finnish Museum of Natural History (LUOMUS), University of Helsinki, Finland Show Profile Dr Kyung Min Lee is the Head of the DNA laboratory and University Researcher at the Finnish Museum of Natural History (LUOMUS), University of Helsinki, Finland. Her expertise lies in molecular phylogenetics and systematics, with a particular focus on biodiversity research utilising old museum collections. Dr Lee is dedicated to unraveling genome-scale biodiversity patterns, exploring cryptic/over-split species, and applying “museomics” to tackle taxonomically challenging species groups. She is pioneering a novel approach using machine learning for more objective species delimitation. She received PhD degree from the Department of Biology at Chungnam National University, Daejeon, Korea. Following her doctoral studies, she pursued postdoctoral research at Ghent University in Belgium, supported by a fellowship from the NRF funding. Later, in 2015, she moved to Finland to join the University of Oulu, where she focused on the study of the next-generation taxonomy in various organisms. In 2020, Dr Lee was recruited to LUOMUS, Helsinki, where she continues her academic endeavors to date.
Synopsis	(Science and Technology Session: 50 min, Roundtable Discussion: 50 min) Innovative Technology for Protein Engineering and Science (chaired by Dr Eui-Jeon Woo) This session highlights cutting-edge advancements in protein engineering and science, featuring de novo mini binder proteins for therapeutics, ribosomal exit tunnel engineering to modulate protein folding, and enzyme optimization for industrial applications. These presentations demonstrate significant progress with broad implications for both science and industry. Roundtable Discussion (moderated by Dr Kyung Min Lee) - *Please be advised that this roundtable discussion will be held in Korean. (본 패널토론은 한국어로 진행 될 예정입니다.) This round table discussion session aims to be a springboard for a lively discussion in forging a stronger Europe-Korea partnership in biosciences and biotechnology. Key areas of discussion includes but are not limited to harnessing complementary strengths, fostering collaboration, and building a robust ecosystem. Panel list: - Dr. Jang-Seong Kim, President of the Korea Research Institute of Bioscience and Biotechnology (KRIBB). - Prof. Insung Choi, Department of Chemistry, and Bio and Brain Engineering, Korea Advanced Institute of Science & Technology (KAIST). - Prof. Mok Hun, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, Ireland.
Speakers	DR. AHN, Minkoo (School of Biochemistry, University of Bristol, Bristol, UK) [ 09:00 - 09:25 ] Title: Rational Ribosome Engineering to Modulate Protein Folding and Expression DR. WOO, Eui-jeon (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) [ 09:25 - 09:50 ] Title: Computational Protein Design for Biopharmaceuticals and Industrial Enzyme DR. KIM, Jang-seong (Korea Research Institute of Bioscience and Biotechnology (KRIBB)) [ 09:50 - 10:40 ] Title: Roundtable Discussion with Dr Kim, Jang-Seong (KRIBB), Profs Choi, Insung (KAIST) and MOK, K. Hun (Trinity College Dublin)

[LH1] At the Front Line of Biophysics

Date / Time	2024-07-30 11:00 -- 12:40
Room	OC1.04
Conveners / Chairs	DR. LEE, Seung Seo Associate Professor, School of Chemistry, University of Southampton, UK Show Profile Dr Seung Seo Lee is Associate Professor in Chemical Biology/Medicinal Chemistry, conducting cutting-edge research projects on antimicrobial resistance and glycoenzymes. Dr Lee obtained his BSc and MSc in chemistry from Seoul National University in South Seoul, Korea. He then worked in the pharmaceutical industry before starting his doctoral study in chemistry at University of British Columbia in Vancouver, Canada. He obtained his PhD under the supervision of Professor Stephen G Withers, studying the reaction mechanism of glycan processing enzymes. After postdoctoral studies at University of Cambridge (Prof. Florian Hollfelder), University of Alberta (Prof. David R Bundle) and University of Oxford (Prof. Benjamin G Davis), he was appointed as an academic staff at University of Southampton, where he has since been working.
Synopsis	This session will present the recent progress in the field of biophysics. Experts from Korea and Europe will discuss how biological problems including cancer, biomaterials and nanobio can be addressed by application of biophysical principles and techniques.
Speakers	PROF. LEE, Jong-bong (Department Of Physics And School Of Interdisciplinary Bioscience & Bioengineering, Postech) [ 11:00 - 11:25 ] Title: Direct and Distant Cellular Communication PROF. KENAR LIM, Necla (Kocaeli University, Türkiye) [ 11:25 - 11:50 ] Title: The role of biophysics in the personalized treatment of cancer DR. BAE, Wooli (University Of Surrey) [ 11:50 - 12:15 ] Title: Self-Assembly of DNA Nanostructures using DNA Origami DR. KIM, Youngchan (University Of Surrey) [ 12:15 - 12:40 ] Title: Quantum Biology Research using Engineered Fluorescence Proteins

[LH2] Excellence with Impact: Disruptive Innovations in the Biomedical Space

Date / Time	2024-07-31 09:00 -- 10:40
Room	OC1.04
Conveners / Chairs	PROF. MOK, K. Hun Trinity College Dublin, Trinity Biomedical Sciences Institute (TBSI), School of Biochemistry & Immunology Show Profile Prof Mok is currently Associate Professor in Biochemistry (Trinity College Dublin), Technical Advisor and IP Holder (HAMLET Pharma AB), Director (ICMRBS), Editorial Board member (Protein Journal, Biomolecules, and BioMed Res Intl) and a member of the EUREKA IEP (Independent Evaluation Panel). His area of interest is in protein folding / misfolding and biomolecular NMR spectroscopy, and has published approx. 70 articles (in journals including Nature, Nature Communications, Nature Immunology, PNAS, and JACS), the inventor of more than 10 registered patents, and recently authored a book, Letters from Dublin (2023). Prof Mok’s expertise in using NMR spectroscopy to elucidate structurally-fluid protein-fatty acid complexes has led to the development of ‘Alpha1’ by start-up company HAMLET Pharma, which has concluded successful Phase I/II studies as a bladder cancer therapeutic (Brisuda A et al, Nature Commun 2021). In addition, he is serving as the technical consultant to two start-up companies, Meta-Flux Ltd (Ireland) and Lmntic Biotech (Korea).
Synopsis	Throughout the history of science, it has been well proven that technological developments – be it in computational science, physics, chemistry, engineering, or mathematics – often drive further understanding and elucidation of biological/medical phenomena. The sheer quantity of Nobel Prizes in Physics or in Chemistry that are awarded to scientists who work on biological problems (whom one would assume to receive Nobel Prizes only in the area of Physiology & Medicine) clearly attests to this. The impact of these discoveries and innovations are now realized through their rapid ‘translation’ – application of these technologies to real world situations and/or to patients – accompanied with commercialization happening at a blindingly fast pace and on the global stage. It is the purpose of this Scientific Session to introduce cutting-edge, disruptive technological advances and show that in many cases, such innovations have brought forth fruits of commercialization. To this end, we will invite scientists and academics who are based in the physical, chemical, and/or computational sciences but who have shown that their innovations can be applied to the biomedical space. In some cases, their work have interested investors who are funding their start-up companies.
Speakers	MR. LEE, Jongmin (University Of Cambridge) [ 09:00 - 09:15 ] Title: Predictive modelling of liquid ingress into disintegrating pharmaceutical tablets MR. LEE, Chanhee (Lmntic Biotech) [ 09:15 - 09:30 ] Title: Micro-magnetophoretic Circuit as Preprocessing Method for Single-cell Genomic Analysis in Universal Usage of CTC Liquid Biopsy DR. CHOI, Jiwoo (Imperial College London) [ 09:30 - 09:50 ] Title: Thermally Drawn Programmable Shape Memory Polymer Fibres for Medical Applications PROF. IM, Hyungsoon (Massachusetts General Hospital) [ 09:50 - 10:15 ] Title: Next-Generation Technologies for Precision Molecular Cancer Diagnostics DR. HONG, Hyobong (ETRI, Creative & Basic Technology Research Division 218, Gajeong-ro, Yuseoung-gu, Daejeon, Rep. of Korea) [ 10:15 - 10:45 ] Title: Magnetic Particle Imaging: An Early Detection System for Cancer and Neurodegenerative Diseases

[LH3] New Ideas and Approaches in Biological Sciences

Date / Time	2024-07-31 11:00 -- 12:40
Room	OC1.04
Conveners / Chairs	DR. LEE, Seung Seo Associate Professor, School of Chemistry, University of Southampton, UK Show Profile Dr Seung Seo Lee is Associate Professor in Chemical Biology/Medicinal Chemistry, conducting cutting-edge research projects on antimicrobial resistance and glycoenzymes. Dr Lee obtained his BSc and MSc in chemistry from Seoul National University in South Seoul, Korea. He then worked in the pharmaceutical industry before starting his doctoral study in chemistry at University of British Columbia in Vancouver, Canada. He obtained his PhD under the supervision of Professor Stephen G Withers, studying the reaction mechanism of glycan processing enzymes. After postdoctoral studies at University of Cambridge (Prof. Florian Hollfelder), University of Alberta (Prof. David R Bundle) and University of Oxford (Prof. Benjamin G Davis), he was appointed as an academic staff at University of Southampton, where he has since been working.
Synopsis	This session will take a look at the challenges and opportunities that all bioscience researchers are facing into the 21st century. The boundary of bioscience has been widening year after year, and it now encompasses material science, data science, digital technology such as computation and artificial intelligence, and . This session will highlight bioscience at the centre of scientific convergence and transformation and how other disciplines are utilized to advance bioscience.
Speakers	PROF. CHOI, Insung (Department of Chemistry, and Bio and Brain Engineering, KAIST, Daejeon, Korea) [ 11:00 - 11:30 ] Title: Single-Cell Nanoencapsulation: Past, Present, and Future PROF. KOH, Won-gun (Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul, Korea) [ 11:30 - 11:50 ] Title: Self-healable double-network hydrogel for new platform to construct biomimetic environment with bottom-up approach PROF. KIM, Won Jong (Department of Chemistry, Postech & OmniaMed, Pohang, Korea) [ 11:50 - 12:10 ] Title: Polymer nanoparticles for mRNA delivery DR. CHOI, Hansol (Harvard Medical School, Boston, MA, USA) [ 12:10 - 12:25 ] Title: Highly Parallel and Programmable Single-molecule force spectroscopy by light-guided patterning DR. BHAK, Ghibom (Department Of Organic Chemistry, The University Of Salamanca, Spain) [ 12:25 - 12:40 ] Title: Sequence-controlled Amphiphilic Polyaspartamide Derivatives for High mRNA Transfection

[LH4] Cutting-Edge Technology to Fight Against Vision-Threatening Diseases

Date / Time	2024-07-31 16:20 -- 18:00
Room	OC1.04
Conveners / Chairs	PROF. RHO, Seungsoo CHA Bundang Medical Center PROF. KIM, Young Kook College of Medicine, Seoul National University
Synopsis	Background and Purpose The eye is the closest window to the central nervous system, and vision loss imposes various constraints on sensory activities due to its impact. Early diagnosis and therapeutic strategies for irreversible vision loss causes such as glaucoma and retinal diseases have garnered significant attention recently, fueled by advancements in AI and Neuroscience. This session aims to introduce the latest technologies for vision preservation, discuss limitations, and explore future directions. Contents 1.Biomaterials ; Glaucoma stands as the most common cause of irreversible blindness globally, with intraocular pressure control being the most potent treatment. However, efforts to overcome the limitations of past implants for pressure control encounter challenges not only of biological origin but also non-biological factors. This session delves into multidisciplinary strategies essential for developing treatments for vision-threatening conditions. 2.Bioinformatics ; Analysis of data for the inhibition of myopia progression and the discovery of biomarkers to suppress glaucoma progression are crucial for future research and experiments. This section explores the bioinformatic aspect of these endeavors. 3.Bioenergetics ; The development of medication regulating the mechanism of optic nerve degeneration has recently yielded significant breakthroughs in in vivo and clinical studies, presenting a fundamental and causal approach to disease onset. Learn about current research findings in bioenergetics, pharmaceutical constraints, and anticipated future areas. Significance and Impact on transforming tomorrow As Isaac Newton suggested, just as we can discuss current research achievements from the shoulders of giants, a bioinformatics-driven approach is crucial for an accurate assessment of past research outcomes in the process of preparing treatments for neurodegenerative conditions leading to irreversible vision loss, such as glaucoma and retinal diseases. Furthermore, in the development of medical therapeutic agents, a bioenergetic approach is particularly critical for neurodegenerative diseases with low energy efficiency. Additionally, a multidisciplinary strategy is essential at this juncture, encompassing the overcoming of medical-industrial constraints, especially in the clinical development of biocompatible biomaterials.
Speakers	PROF. HA, Ahnul (Jeju National University School Of Medicine) [ 16:20 - 16:45 ] Title: Nocturnal Artificial Light Exposure and the Risk of Strabismus, Age-Related Macular Degeneration, and Adverse Birth Outcomes PROF. KIM, Young Kook (Seoul National University College Of Medicine And Hospital) [ 16:45 - 17:10 ] Title: Visual Impairment, Blindness, and a Public Health Approach PROF. PARK, Dong Young (University Of Warwick & University Hospitals Coventry And Warwickshire Nhs Trust) [ 17:10 - 17:35 ] Title: The use of fluorinated gases and quantification of carbon emission for common vitreoretinal procedures PROF. RHO, Seungsoo (Cha Bundang Medical Center, CHA University, Republic of Korea) [ 17:35 - 18:00 ] Title: Neuroprotective effect of nicotinamide-loaded extracellular vesicles against glaucoma

[LH5] Cell plasticity and homeostatsis: How the cells reponse upon different stimuli and stress

Date / Time	2024-08-01 09:00 -- 10:40
Room	OC1.04
Conveners / Chairs	MS. SONG, Yura Université Libre de Bruxelles Show Profile Yura Song obtained her Bachelor's degree in bioinformatics and bioengineering from Soongsil University in 2015, graduating early with academic excellence. She then earned her Master's degree in Biochemistry from Ewha Womans University in 2018. Yura worked as an associate researcher at the National Cancer Center in South Korea from 2015 to 2018, focusing on deciphering genetic markers for predicting gastric cancer metastasis. In 2018, she relocated to Belgium to pursue her Ph.D. at Université Libre de Bruxelles under the supervision of Cédric Blanpain. Her research concentrated on unraveling the gene regulatory networks involved in various types of cancers and the skin homeostasis process. Since April 2023, Yura has been working as a bioinformatician with a focus on constructing gene regulatory networks that control development and cancers, including glandular epithelia and skin.
Synopsis	Our understanding of cell plasticity and homeostasis is crucial to comprehending the remarkable ability of cells to adapt to various stimuli and stress. This session will let you dive into the dynamic nature of cells, focusing on their response mechanisms to different stresses and the subsequent changes in cell character and behavior. In this session, responses to the external stress on different species and different tissues will be discussed. By dealing with the topics from the impact of cellular stress on phenotype changes and the external stresses that influence the microbiome to complex relationship between cell plasticity and cancer initiation, this session will provide a comprehensive view of cellular adaptability. The session highlights include: - Impact: The discussions will unravel the impact of cellular stress on disease initiation, with a focus on the delicate balance between cell plasticity and homeostasis. By understanding how cells react and adapt to stress, we gain insights into potential targets for disease prevention and treatment, particularly in the context of cancer and microbiome-related disorders. - Innovation: This session showcases innovative research on the molecular mechanisms underlying cellular responses to stress. By deciphering how cells revert to a multipotent state and alter their phenotype, we open avenues for the development of novel therapeutic approaches, early detection methods, and potentially transformative interventions for various diseases. - Connectivity: Fostering a collaborative environment, this session brings together experts from diverse fields, including cell biology, oncology, and microbiome research. By encouraging the exchange of ideas and knowledge, we aim to build connections that will accelerate the translation of fundamental discoveries into clinical applications, benefiting society as a whole.
Speakers	DR. OH, Jeong-joo (Department Of Bionanoscience, Kavli Institute Of Nanoscience, Delft University Of Technology) [ 09:00 - 09:20 ] Title: Biologically grown living materials for biotechnological applications DR. LEE, Mungyu (Department Of Biotechnology, Delft University Of Technology) [ 09:20 - 09:40 ] Title: Strategies for Enhancing Cell Activity and Stability in Bioprocess Operations MISS. SONG, Yura (Université Libre De Bruxelles (ULB)) [ 09:40 - 10:00 ] Title: Cell type and stage specific transcriptional, chromatin and cell-cell communication landscapes in the mammary gland DR. KIM, Minchul (Igbmc) [ 10:00 - 10:20 ] Title: Formation and maintenance of muscle domains DR. HAM, Seokjin (CNIO) [ 10:20 - 10:40 ] Title: Transcriptomic dissection analysis of longevity factors acting in insulin/IGF-1 signaling in Caenorhabditis elegans

[LH6] Exploring Multifaceted Approaches to Reducing the Cancer Burden and Promoting Health

Date / Time	2024-08-01 11:00 -- 12:40
Room	OC1.04
Conveners / Chairs	DR. NOH, Hwayoung Researcher, Department of Cancer Prevention and Environment, INSERM U1296, Leon Berard Cancer Center (CLB), France Show Profile Hwayoung Noh holds a B.S., M.Sc., and Ph.D. in nutrition from Seoul National University, Korea. She undertook her postdoctoral fellowship in the Nutrition and Metabolism Branch, IARC-WHO, Lyon, France. Currently, she is a researcher in the Department of Cancer Prevention and Environment, CLB, Lyon, France. Her main research interests are focused on 1) understanding the impact of diet, nutrition and other lifestyle factors (e.g., physical activity, body shape) in human health and disease development, particularly cancer; 2) utilizing various biomarkers including “-omics” data (e.g., microbiome and metabolomics), to investigate underlying mechanisms.
Synopsis	Cancer continues to impose a significant burden worldwide, with approximately 20 million new cases and 10 million cancer-specific deaths estimated in 2022 (GLOBOCAN, International Agency for Research on Cancer, IARC-WHO). The global cancer burden remains a pervasive challenge, affecting individuals and communities across diverse lifestyle, genetic, socioeconomic, and demographic backgrounds. In light of this challenge, the proposed session will explore various approaches in recent scientific undertakings for cancer prevention and care. The session will feature presentations and discussions from varied outstanding experts in the field of cancer research from Korea and Europe. By examining these multifaceted approaches, this session aims to inspire collaborative efforts between researchers and policymakers to address the complex challenges posed by cancer and promote positive health outcomes.
Speakers	DR. STEPIEN, Magdalena (Project Leader, Joint Research Centre of The European Commission (EC-JRC), Italy) [ 11:00 - 11:25 ] Title: Supporting Europe's Beating Cancer Plan- its Flagship Initiatives at the Joint Research Centre of the European Commission (EC-JRC) PROF. KIM, Ji Hye (Kyung Hee University) [ 11:25 - 11:50 ] Title: Plant-based Dietary Patterns and Cancer Prevention PROF. LIM, Hyun Soo (Sakarya University of Applied Science Turkey) [ 11:50 - 12:15 ] Title: Mechanism and Technology of Photodynamic Therapy and Its Application in Laser Induced Cancer Treatments DR. NOH, Hwayoung (Departement of Prevention Cancer Environment, Inserm U1296, Léon Bérard Comprehensive Cancer Centre (CLB), Lyon, France) [ 12:15 - 12:30 ] Title: Impact of Physical Activity Interventions on Cancer-Related Sequelae: Insights from the Léon Bérard Comprehensive Cancer Center MR. HEO, Danhui (Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary) [ 12:30 - 12:40 ] Title: Impact of Portal/Superior Mesenteric Vein Abutment Angle on Prognosis in Resectable Pancreatic Cancer (Poster Flash Presentation)

[LH7] Aging and Diseases

Date / Time	2024-08-01 14:00 -- 15:40
Room	OC1.04
Conveners / Chairs	PROF. LEE, Soyoung Johannes Kepler University, Austria Show Profile Soyoung Lee received B.S. and M.S. at KAIST, Korea, and continued her study at SUNY-Stony Brook and the Cold Spring Harbor Laboratory, NY, USA. Since her postdoctoral fellowship period at the Charité – Berlin University Medicine, her research has been focusing on the senescence of cancer cells during tumor development and under therapy, utilizing mouse models and a broad spectrum of molecular biological and genetic methods. Recently, her research field expanded to virus infection as a trigger of cellular senescence under other disease conditions. Since October 2021, she is leading the Institute of Tumor Biology in the medical faculty of JKU Linz, Austria. Her scientific core expertise is tumor biology complemented with translational approach.
Synopsis	Senescence is the aging process of both organisms and the cells composing them. At the cellular level, senescence operates as a self-defense mechanism, in response to the acculation of damages induced by various types of stress, leading to reduced (or different) functionality and eventually to permanent cell cycle arrest. Consequently, the accumulation of senescent cells contribute to age-related diseases in human body, including cardiovascular disorders, neurodegenerative conditions, and cancer. Recent advancements in the field, particularly the development of senolytics, targeting senescent cells, is attracting a lot of attention in the scientific community, not only in regard of aging and also in disease research. Understanding the molecular and cellular mechanism of senescence is fundamental for comprehending how the human body ages and is the foundation for developing tools to mitigate the aging process. It will offer innovative strategies to enhance healthspan and address the challenges posed by an aging population.
Speakers	PROF. SCHMITT, Clemens (Medical Department of Hematology and Oncology Kepler Universitätsklinikum, Johannes Kepler University, Linz, Austria) [ 14:00 - 14:30 ] Title: Senescence in cancer – clinical opportunities and challenges DR. HAN, Ju Yeon (European Molecular Biology Laboratory) [ 14:30 - 14:50 ] Title: Understanding plasticity in mouse development PROF. GIL, Jesús (Imperial College London and MRC Laboratory of Medical Sciences) [ 14:50 - 15:20 ] Title: Targeting senescence for therapeutic benefit DR. BYUN, Junho (Ghent University) [ 15:20 - 15:40 ] Title: Disease-Selective Nanomedicines for the Treatment of Fibrosis and Obesity

[LH8] One Health: Understanding Diseases and Pathogens

Date / Time	2024-08-01 16:00 -- 17:40
Room	OC1.04
Conveners / Chairs	DR. HAN, Sojung Postdoctoral researcher, University of Vienna, Vienna, Austria Show Profile 2016-2019 PhD, Pompeu Fabra University, Barcelona, Spain 2019-2020 Postdoctoral researcher, Pompeu Fabra University, Barcelona, Spain 2023- Postdoctoral researcher, University of Vienna, Austria
Synopsis	Diseases have been a major threat in humankind. The concept of hygiene, improved medical diagnoses and treatments, and vaccination have increased human survival rates until adulthood and prolonged the lifespan enormously. The way we perceive diseases is also changing as knowledge accumulates. For example, cancer is in many cases not an ultimate threat anymore, but can be healed or at least attenuated to a large extent. The complex genetic landscape of the cancer condition is better understood, guiding the path to new treatments. Many human diseases are caused by pathogens, which are often not restricted to humans but can also be transmitted to and from other species, recently exemplified by the COVID-19 pandemic. Analysing the natural reservoirs of pathogens and the way they jump from one species to another will allow us to be better prepared for future epidemic events. In this session, we will introduce and discuss some of the most recent developments in human health and disease.
Speakers	DR. PARK, Solip (Cnio, Madrid) [ 16:00 - 16:20 ] Title: Deciphering context-specific cancer fitness levels: unraveling the key driver genes in tumor progression DR. SEO, Hwi Won (Korea Research Institute Of Bioscience And Biotechnology) [ 16:20 - 16:40 ] Title: Indirect attenuation of Staphylococcus aureus skin infection by modulation of pathogen helper bacteria DR. GWEON, Hyun Soon (University Of Reading) [ 16:40 - 17:00 ] Title: Dynamic Shifts and Resilience of Sink Drain Bacterial Communities PROF. KIM, Jongil (KAMC / SNU Medicine) [ 17:00 - 17:20 ] Title: Overseas Training Support Project: Enhancing Global Research Competencies of Biomedical Talents DR. HAN, Sojung (University Of Vienna, Vienna, Austria) [ 17:20 - 17:40 ] Title: Looking into divergent virus genomes beyond humans

PROGRAMME